Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities
Abstract Background Non-alcoholic steatohepatitis (NASH) is Makeup a common disease and feeding mice a methionine-choline-deficient (MCD) diet is a frequently used model to study its pathophysiology.Genetic and environmental factors influence NASH development and liver lipid content, which was studied herein using C57BL/6 J mice bred in two differe